While graying hair might feel like just one more unpleasant symptom of aging, new research reveals that it may actually be the result of a biological process that defends against cancer risk.
In a study led by the University of Tokyo and published earlier this month in the journal Nature Cell Biology, researchers used lab mice to investigate how a type of stem cell reacts to DNA damage, revealing a connection between hair graying and a form of skin cancer called melanoma.
DNA damage, aging, and cancer
Our body’s cells are continuously faced with internal and environmental agents that can cause DNA damage, which plays a role in both aging and cancer. Scientists have struggled to pin down the specifics of this role, especially how damaged stem cells impact tissue health in the long term.
Stem cells are cells that can self-renew (make more of themselves) and differentiate (turn into other cells). Within this context, the team specifically analyzed melanocyte stem cells (McSCs)—stem cells that produce mature melanocytes, pigment-producing cells that give color to hair and skin. In mammals, McSCs live in hair follicles in the form of immature melanoblasts (melanocytes’ precursors), where they perpetuate pigmentation.
Disclaimer
The information contained in South Florida Reporter is for general information purposes only.
The South Florida Reporter assumes no responsibility for errors or omissions in the contents of the Service.
In no event shall the South Florida Reporter be liable for any special, direct, indirect, consequential, or incidental damages or any damages whatsoever, whether in an action of contract, negligence or other tort, arising out of or in connection with the use of the Service or the contents of the Service. The Company reserves the right to make additions, deletions, or modifications to the contents of the Service at any time without prior notice.
The Company does not warrant that the Service is free of viruses or other harmful components
